You may have a podcast with one host, a podcast with a co-host, or other co-hosts.
This depends on what you want.
A podcast with many co-hosts with great knowledge of the topic (for example Funnel Fridays) will be more popular than a podcast with an amateur host.
Likewise, a Podcast led by one very good and professional host would be more successful than one that is run by amateur less knowledgeable co-hosts.
Make sure that the host or hosts of your podcast are interested in the podcast themes and topics.